ইঙ্গিত
Brinz T is used to lower intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension when a single medicine alone does not reduce IOP enough.
⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।
ফার্মাকোলজি
Brinzolamide is a potent inhibitor of human carbonic anhydrase II (CA-II), the predominant iso-enzyme found in the eye. By inhibiting CA-II in the eye's ciliary processes, it decreases aqueous humour secretion, presumably by slowing the formation of bicarbonate ions and thereby reducing sodium and fluid transport. Timolol is a non-selective beta-adrenergic blocking agent with no intrinsic sympathomimetic, direct myocardial depressant, or membrane-stabilising activity. Tonography and fluorophotometry studies in humans suggest that its predominant action is to reduce aqueous humour formation, along with a slight increase in outflow facility. Both components lower elevated intraocular pressure (IOP) mainly by reducing aqueous humour secretion, though they do so through different mechanisms of action. Together, the two active substances produce a greater reduction in IOP than either one achieves on its own.
Pregnancy & Breastfeeding
Pregnancy Category C. There isn't enough data on Brinzolamide use in pregnant women, though animal studies have shown reproductive toxicity, so the risk to humans remains unknown. Information from a limited number of pregnancies exposed to Timolol eye drops shows no adverse effects on the pregnancy or the baby's health, though one case of foetal bradycardia and arrhythmia has been reported in a woman using Timolol eye drops. It isn't known whether Brinzolamide passes into human breast milk, although animal studies have shown it is excreted in milk. Timolol does pass into human breast milk; however, at the therapeutic doses used in this combination, no effects on breastfed infants are expected. Brinzolamide + Timolol eye drops can be used while breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
ডোজ নির্দেশিকা
⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।
পার্শ্বপ্রতিক্রিয়া ও পারস্পরিক ক্রিয়া
পার্শ্বপ্রতিক্রিয়া
No side-effect data recorded yet.