ইঙ্গিত ও ব্যবহার
Vaxitet-IG is used to provide short-term (passive) immunity for both preventing and treating tetanus.
ডোজ নির্দেশিকা
শুধুমাত্র নির্দেশিকা তথ্য
প্রদর্শিত ডোজগুলি সরকারি উৎসের সাধারণ নির্দেশিকা। ব্যক্তিগতকৃত ডোজের জন্য সর্বদা আপনার ডাক্তার বা ফার্মাসিস্টের পরামর্শ নিন।
Adults:
Dosage Prophylaxis of tetanus: Tetanus Antitoxin (equine) should not be used in the routine treatment of traumatic wounds. It is given prophylactically to persons at the risk of tetanus infection by infected wounds or severe wounds. For prophylaxis after injury, non-immune or partially immune persons may be given 3,000 to 5,000 units of tetanus antitoxin subcutaneously or intramuscularly. If 24 hours have passed since the wound occurred, the dose is 3,000 III. In crush wounds or wounds contaminated with soil or other foreign bodies, the dose is 10,000 to 20,000 III. For persons below 30 kg the dosage is 1,500 IU. Active immunization with Adsorbed Tetanus vaccine should be given simultaneously with the use of this preparation or a booster injection of Adsorbed Tetanus vaccine should be given if the patient has previously been immunized.Treatment: Therapy should be given as soon as possible after the appearance of symptoms of the disease. Therapeutic dose not less than 3000 IU. Depending on the severity, the dose may vary from 50,000 to 100,000 IU of tetanus antitoxin for hospitalized patients given partially by intravenous route and the rest of the dose intramuscularly.
পার্শ্বপ্রতিক্রিয়া
Hypersensitivity reactions can occur after an injection of any serum derived from animals. In rare cases, this may show up as low blood pressure, breathing difficulty, or hives, and should be managed with adrenaline, sometimes alongside antihistamine and corticosteroid treatment. Serum sickness can also develop 7 to 10 days after receiving an animal-derived serum, presenting with fever, vomiting, diarrhoea, bronchospasm, and hives.
সতর্কতা ও নিষেধাজ্ঞা
Warnings & Precautions
If there is no history of previous serum injection or allergic reaction, the dose of serum may be given intramuscularly. If the patient is subject to allergic diseases, a trial dose of 0.2 ml (diluted 1:10 if preferred) of the serum should be given subcutaneously; if no general reaction develops during an interval of 30 minutes, the main dose may be given intramuscularly. The patient must be kept under observation for at least 30 minutes after the injection, and adrenaline should be kept in readiness for emergency use. In all urgent cases, the intravenous route is indicated, but it should never be used unless a preliminary intramuscular injection, given at least 30 minutes beforehand, has been tolerated. For intravenous use, the serum should be at room temperature, the injection should be given very slowly, and the patient should be lying down during the injection and for at least an hour afterwards.
নিষেধাজ্ঞা
Injection of the antitoxin to persons with a history of allergic reactions to equine protein and to allergic individuals is contraindicated.