ইঙ্গিত ও ব্যবহার
Vasopressin injection is used for: Vasopressin injection is indicated to increase blood pressure in adults with vasodilatory shock. Vasopressin as an early adjunct to norepinephrine for patients with septic shock could be beneficial to patient outcomes. Post-cardiotomy shock Septic shock.
ডোজ নির্দেশিকা
শুধুমাত্র নির্দেশিকা তথ্য
প্রদর্শিত ডোজগুলি সরকারি উৎসের সাধারণ নির্দেশিকা। ব্যক্তিগতকৃত ডোজের জন্য সর্বদা আপনার ডাক্তার বা ফার্মাসিস্টের পরামর্শ নিন।
প্রাপ্তবয়স্ক:
0.01 - 0.03 Units/Min.Dilute 20 units/mL single-dose vial contents with normal saline (0.9% sodium chloride) or 5% dextrose in water (D5W) to either 0.1 units/mL or 1 unit/mL for intravenous administration. Discard unused diluted solution after 18 hours at room temperature or 24 hours under refrigeration.Post-cardiotomy shock: 0.03 to 0.1 units/minute. (The recommended starting dose)Septic shock: 0.01 to 0.07 units/minute. (The recommended starting dose)
পার্শ্বপ্রতিক্রিয়া
Common Side Effects: Headache Nausea, vomiting Abdominal cramping Increased blood pressure Water retention and hyponatremia (low sodium levels) Serious Side Effects: Myocardial ischemia or infarction: Due to vasoconstriction, especially in patients with pre-existing heart disease. Severe hyponatremia: Can lead to water intoxication, seizures, and altered mental status. Arrhythmias: Increased risk of arrhythmias due to fluid shifts and electrolyte imbalances. Gangrene: If extravasation occurs during infusion, tissue necrosis may develop at the injection site.
সতর্কতা ও নিষেধাজ্ঞা
সতর্কতা ও সাবধানতা
Electrolyte Imbalance: Close monitoring of electrolytes is required, particularly for sodium levels. Excessive water retention can lead to hyponatremia, which can cause seizures, coma, or even death.Vasopressin-Induced Ischemia: Because of its vasoconstrictor properties, Vasopressin should be used cautiously in patients with ischemic conditions (e.g., coronary artery disease, peripheral vascular disease).Extravasation Risk: When administered intravenously, extravasation (leakage of the drug into surrounding tissues) should be avoided, as it can lead to necrosis and other serious tissue damage.
নিষেধাজ্ঞা
Hypersensitivity: Known hypersensitivity to vasopressin or any of its components.Chronic Renal Failure: In cases of severe renal disease or where fluid retention is contraindicated.Severe Hypertension: Vasopressin should be avoided in patients with significant hypertension unless there is an urgent need.Coronary Artery Disease: Caution in patients with coronary artery disease, as vasoconstriction can worsen ischemia.