TTvax

Adults:

Adsorbed Tetanus Vaccine: Dosage Reference (Adults) The full basic course of immunization against tetanus consists of two primary doses of 0.5 ml given at least four weeks apart, followed by a third dose 6 to 12 months later. To maintain a high level of immunity, further 0.5 ml booster doses are recommended at every feasible interval (for adults, usually every 5 to 10 years). Protection of the newborn against tetanus: To prevent neonatal tetanus, Tetanus Toxoid vaccine is recommended for immunizing women of childbearing age, and especially pregnant women. Tetanus Toxoid vaccine may be safely administered during pregnancy and should be given to the mother at first contact or as early as possible in the pregnancy. A five dose schedule is recommended for previously unimmunized women of childbearing age: after the basic course of immunization with three doses, two additional booster doses should be given, at least one year after the previous dose or during a subsequent pregnancy. Vaccination of the injured person: For those who have proof of either completing their course of primary immunizations containing tetanus toxoid or receiving a booster shot within the previous 5 years, no additional dose of tetanus toxoid is recommended. If more than 5 years have elapsed and infection with tetanus due to injury or another cause is suspected, 0.5 ml of Tetanus Toxoid vaccine should be given immediately. Where the immunization history is inadequate, 1500 IU (3000 old AU) of tetanus antiserum and 0.5 ml of Tetanus Toxoid vaccine should be injected with separate syringes into different body sites (if available, 250 units of tetanus immune globulin of human origin can be substituted for the tetanus antiserum). A second 0.5 ml dose of Tetanus Toxoid vaccine is recommended after 2 weeks, and a third dose after a further 1 month. A note of caution: if horse origin tetanus antiserum is used in prophylaxis, the patient should be tested for sensitivity to horse serum protein before it is given. It is desirable to have 1 ml of Adrenaline solution (1:1000) immediately available, and the normal precautions for injecting antitoxins should be followed. Method of inoculation: This should be injected intramuscularly into the deltoid muscle in women and older children. Only sterile needles and syringes should be used for each injection. The vaccine should be well shaken before use. Once opened, multi dose vials should be kept between 2°C and 8°C. Reactions: Reactions are generally mild and confined to the site of injection. Some inflammation may occur, together with transient fever, malaise and irritability. Occasionally a nodule may develop at the site of injection, but this is rare. Increased severity of reactions to vaccination may be observed in people who have had many booster immunizations.