Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
সব দামের পরিবর্তন →ইঙ্গিত ও ব্যবহার
Tojak এর জন্য নির্দেশিত:
ডোজ নির্দেশিকা
শুধুমাত্র নির্দেশিকা তথ্য
প্রদর্শিত ডোজগুলি সরকারি উৎসের সাধারণ নির্দেশিকা। ব্যক্তিগতকৃত ডোজের জন্য সর্বদা আপনার ডাক্তার বা ফার্মাসিস্টের পরামর্শ নিন।
Adults:
Rheumatoid Arthritis: The usual dose is Tofacitinib 5 mg twice daily, or Tofacitinib 11 mg once daily. For patients with moderate to severe renal impairment or moderate hepatic impairment, the recommended dose is Tofacitinib 5 mg once daily. Psoriatic Arthritis (used together with nonbiologic DMARDs): The usual dose is Tofacitinib 5 mg twice daily, or Tofacitinib 11 mg once daily. For patients with moderate to severe renal impairment or moderate hepatic impairment, the recommended dose is Tofacitinib 5 mg once daily. Ulcerative Colitis: The usual dose is Tofacitinib 10 mg twice daily for at least 8 weeks, followed by 5 mg or 10 mg twice daily. If adequate therapeutic benefit is not achieved, the 10 mg twice daily dose should be discontinued after 16 weeks. The lowest effective dose should be used to maintain response.
পার্শ্বপ্রতিক্রিয়া
The most commonly reported side effects during the first 3 months of controlled clinical trials (occurring in at least 2% of patients taking Tofatin XR alone or together with DMARDs) were upper respiratory tract infections, headache, diarrhea and nasopharyngitis.
সতর্কতা ও নিষেধাজ্ঞা
Warnings & Precautions
Serious Infections: Do not start Tofatin XR treatment during an active serious infection, including infections that are localized. Gastrointestinal Perforations: Use it cautiously in patients who may be at higher risk. Laboratory Monitoring: Regular lab checks are advised, since Tofatin XR can affect lymphocyte, neutrophil, hemoglobin, liver enzyme and lipid levels. Immunizations: Avoid giving live vaccines alongside Tofatin XR. Treatment should not be started if the absolute lymphocyte count is below 500 cells/mm3, the absolute neutrophil count (ANC) is below 1000 cells/mm3, or hemoglobin is below 9 gm/dL.