Lozicum

Adults:

Lorazepam is taken by mouth. For best results, the dose, how often it is taken, and how long treatment continues should be tailored to each patient's response. The usual range is 2 to 6 mg a day in divided doses, with the largest dose taken at bedtime, though the largest single dose may range from 1 to 10 mg a day. For anxiety, most patients need an initial dose of 2 to 3 mg a day, taken twice or three times daily. For elderly or frail patients, an initial dose of 1 to 2 mg a day in divided doses is recommended, adjusted as needed and tolerated. For insomnia, 1 to 2 mg is taken before bedtime; as a premedicant, 1 to 2 mg is given the night before surgery and again 1 to 2 hours before surgery. Lorazepam injection can be given intravenously or intramuscularly. For premedication in adults: 0.05 mg/kg (3.5 mg for an average 70 kg person), given by IV 30 to 45 minutes before the procedure, or by IM 60 to 90 minutes before. For acute anxiety in adults: 0.025 to 0.03 mg/kg (1.75 to 2.1 mg for an average 70 kg person), repeated every 6 hours. For status epilepticus in adults: 4 mg intravenously; in children: 2 mg intravenously. For intramuscular use, undiluted lorazepam injection should be given. For intravenous use, it must be diluted with an equal volume of a compatible solution, such as sterile water for injection, sodium chloride injection, or 5% dextrose injection. The rate of injection should not exceed 2 mg per minute.