ইঙ্গিত ও ব্যবহার
Gadosol is indicated for intravenous use with magnetic resonance imaging (MRI) in brain (intracranial), spine and associated tissues in adult and pediatric patients (2 years of age and older) to detect and visualize areas with disruption of the blood brain barrier (BBB) and/or abnormal vascularity.
ডোজ নির্দেশিকা
শুধুমাত্র নির্দেশিকা তথ্য
প্রদর্শিত ডোজগুলি সরকারি উৎসের সাধারণ নির্দেশিকা। ব্যক্তিগতকৃত ডোজের জন্য সর্বদা আপনার ডাক্তার বা ফার্মাসিস্টের পরামর্শ নিন।
প্রাপ্তবয়স্ক:
For adult and pediatric patients (including term neonates), the recommended dose of Gadosol is 0.2 mL/kg (0.1 mmol/kg) body weight administered as an intravenous bolus injection, manually or by power injector, at a flow rate of approximately 2 mL/second for adults and 1- 2 mL/second for pediatric patients. Table 1 provides weight-adjusted dose volumes. To ensure complete injection of Gadosol the injection may be followed by normal saline flush. Contrast MRI can begin immediately following Gadosol injection.
পার্শ্বপ্রতিক্রিয়া
The most frequent adverse reactions in clinical studies were nausea, headache, injection site pain, injection site coldness, and burning sensation.
সতর্কতা ও নিষেধাজ্ঞা
সতর্কতা ও সাবধানতা
Nephrogenic Systemic Fibrosis has occurred in patients with impaired elimination of GBCAs. Higher than recommended dosing or repeat dosing appear to increase the risk. Hypersensitivity: Anaphylactoid/anaphylactic reactions with cardiovascular, respiratory or cutaneous manifestations, ranging from mild to severe, including death, have uncommonly occurred. Monitor patients closely for need of emergency cardiorespiratory support.