ইঙ্গিত ও ব্যবহার
Yonex is indicated for the treatment of acute or chronic infections caused by sensitive strains of certain gram-negative bacilli. It is particularly indicated in the infection caused by sensitive strains of Pseudomonas aeruginosa. Yonex is not indicated for infections due to Proteus ... Read moreYonex is indicated for the treatment of acute or chronic infections caused by sensitive strains of certain gram-negative bacilli. It is particularly indicated in the infection caused by sensitive strains of Pseudomonas aeruginosa. Yonex is not indicated for infections due to Proteus or Neisseria. Yonex is very effective in the treatment of infections due to the following gram-negative organisms: Enterobacter aerogenes, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa.
ডোজ নির্দেশিকা
শুধুমাত্র নির্দেশিকা তথ্য
প্রদর্শিত ডোজগুলি সরকারি উৎসের সাধারণ নির্দেশিকা। ব্যক্তিগতকৃত ডোজের জন্য সর্বদা আপনার ডাক্তার বা ফার্মাসিস্টের পরামর্শ নিন।
প্রাপ্তবয়স্ক:
Dosage Maintenance dose: 9 MIU/day in 2-3 divided doses. In patients who are critically ill, a loading dose of 9 MIU should be administered.Renal impairment patients: Dose adjustments in renal impairment patients are necessary. Dose reductions are recommended for patients with creatinine clearance < 50 ml/min. Twice daily dosing is recommended. Creatinine clearance <50-30 ml/min: daily dose 5.5-7.5 MIU Creatinine clearance <30-10 ml/min: daily dose 4.5-5.5 MIU Creatinine clearance <10 ml/min: daily dose 3.5 MIU Haemodialysis (HD) patients: No-HD days: 2.25 MIU/day (2.2-2.3 MIU/day). HD days: 3 MIU/day (Should be given after the HD session) Twice daily dosing is recommended. Pediatric population: The dose should be based on lean body weight. Children ≤40 kg: 75,000-150,000 IU/kg/day divided into 3 doses. Children >40 kg: >150,000 IU/kg/day has been reported in children with cystic fibrosis. Hepatic impairment patients: There are no data in patients with hepatic impairment. Caution is advised when administering colistimethate sodium in these patients.
পার্শ্বপ্রতিক্রিয়া
The following adverse reactions have been reported: gastrointestinal upset, tingling of extremities and tongue, slurred speech, dizziness, vertigo and paresthesia, generalized itching, urticaria and rash, fever, increased blood urea nitrogen (BUN), elevated creatinine and decreased creatinine clearance, respiratory distress and apnea, nephrotoxicity and decreased urine output.
সতর্কতা ও নিষেধাজ্ঞা
সতর্কতা ও সাবধানতা
Yonex should be used with caution in patient with impaired renal function. When actual renal impairment is present, Yonex may be used, but the greatest caution should be exercised and the dosage should be reduced in proportion to the extent of the impairment. Yonex should be used with caution in neonates, infants and children.
নিষেধাজ্ঞা
The use of Colistimethate Sodium Parenteral is contraindicated for patients with a history of sensitivity to the drug or any of its components.