ইঙ্গিত ও ব্যবহার
Caprolex is used to treat excessive bleeding after surgery, especially in procedures where significant blood loss is expected, such as cardiac surgery. It can be given by mouth or by injection into a vein. A meta-analysis found that lysine analogs like Caprolex significantly reduced blood loss in patients undergoing coronary artery bypass grafting. Caprolex can also be used to treat overdose or toxic effects from the thrombolytic medicines tissue plasminogen activator and streptokinase.
ডোজ নির্দেশিকা
শুধুমাত্র নির্দেশিকা তথ্য
প্রদর্শিত ডোজগুলি সরকারি উৎসের সাধারণ নির্দেশিকা। ব্যক্তিগতকৃত ডোজের জন্য সর্বদা আপনার ডাক্তার বা ফার্মাসিস্টের পরামর্শ নিন।
Adults:
Dosage of Aminocaproic acid must be adjusted to the individual case according to the severity of the bleeding episode. It should be kept in mind that Aminocaproic acid is cleared rapidly through the kidneys, so administration must be repeated every 4 to 6 hours. The average dose is 8 to 16 grams a day, that is, 1 ampule of Aminocaproic acid depending on the case, every 6 hours. Aminocaproic acid is equally effective when taken by mouth or given by intravenous injection. In particularly severe cases, or when a high blood concentration needs to be reached quickly, it is advisable to begin treatment intravenously, with a slow injection of two Aminocaproic acid ampules 30 to 60 minutes apart, then continuing with divided doses until a total of 20 to 25 grams is reached over 24 hours. In all cases, the drug should be continued until all symptoms have completely resolved. Aminocaproic acid may be given intravenously after suitable dilution in physiological saline solution.
পার্শ্বপ্রতিক্রিয়া
Mild muscle pain or weakness, headache, and tiredness can occur. Some people notice nausea, vomiting, stomach pain, or diarrhea. In men, the amount of semen released during orgasm may decrease. A stuffy nose and watery eyes are also possible, along with vision changes or ringing in the ears. A mild skin rash may develop as well.
সতর্কতা ও নিষেধাজ্ঞা
Warnings & Precautions
Safety and effectiveness in patients under 18 years of age have not been established.
নিষেধাজ্ঞা
Aminocaproic acid should not be given if there is any evidence of an active clotting process within the blood vessels. If it isn't clear whether bleeding is due to primary fibrinolysis or disseminated intravascular coagulation (DIC), this needs to be sorted out before Aminocaproic Acid Injection is given, since the two conditions call for different management. A few tests can help tell them apart. Platelet count is typically low in DIC but stays normal in primary fibrinolysis. The protamine paracoagulation test comes back positive in DIC, seen as a precipitate forming when protamine sulfate is added to citrated plasma, whereas it is negative in primary fibrinolysis. The euglobulin clot lysis test, on the other hand, is abnormal in primary fibrinolysis but normal in DIC. If DIC is present, Aminocaproic Acid Injection should not be given unless heparin is administered alongside it.