Asmaloc SR

Adults:

Theophylline dosing must be tailored to each person, guided by measurements of peak theophylline levels in the blood, so that the dose gives the greatest possible benefit with the least risk of side effects. Most sustained release products can be taken every 12 hours in adults, although some children whose livers break down theophylline unusually fast may need a dose every 8 hours. The recommended maintenance doses within the accepted therapeutic range are as follows. For those aged 16 years or older, 10 mg per kg per day, not exceeding 900 mg per day. For ages 12 to 15 years, 13 mg per kg per day. For ages 9 to 11 years, 16 mg per kg per day. For ages 1 to 8 years, 24 to 24 mg per kg per day. For ages 6 months to 1 year, 12 to 18 mg per kg per day. For ages 1 to 6 months, 10 mg per kg per day. Regarding use in children, theophylline is cleared from the body very slowly in newborns. In pediatric patients, doses must be chosen with great care and blood theophylline levels must be monitored closely.